Irritable Bowel Syndrome Message Boards | Histamine intolerance:Diamine Oxidase deficiency

I had printed off the internet a high histamine food list too, a very long time ago before this diet, but things didn't totally click with it at that time. I asked the GI why just 1/4 Benedryl antihistamine seemed to help and he just said well some people take it to relax....A naturopathic doctor told me it confuses the body. I just thought if I built up my probios ibs would stop, but it didn't. The longer cultured high probio yogurt I made was high in histamine as with fermented foods..things got worse back then, even though quiting yogurt and starting capsule probios which don't fair well with me in high cfu counts. For the last 2 1/2 days I've been taking 1/day of Zyrtec antihistamine and have felt pretty dang good. That could mean one is deficient in the enzyme diamine oxidase. I read somewhere people can get a rebound effect with anti-histamines. So would rather just try the enzyme soon.Expensive though..

I just read this from http://www.allergynutrition.com/wp-content/uploads/2014/05/Histamine-DAO-and-Probiotics-Revised.pdf:
Focus of the Proposed Research: Diamine oxidase activity If active diamine oxidase could be supplied to the human digestive tract from a probiotic source, it may be possible to reduce the level of histamine entering the body from the digestive tract. Some preliminary research indicates that certain strains of bacteria, such as species of Lactobacillus, Leuconostoc, Escherichia faecium, Weisella and Sarcina can produce diamine oxidase (Dapkevicius et al 2000; Leuschner et al 1998). It is possible that there may be other micro-organisms capable of synthesising the enzyme, which could be exploited in the production of a probiotic food able to deliver the deficient enzyme to the human gut.

Edited by sgcray (05/17/16 12:46 PM)

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