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There is little evidence to support this theory, and no evidence that so-called 'treatments' for 'leaky gut syndrome', such as nutritional supplements and a gluten-free diet, have any beneficial effect for most of the conditions they are claimed to help.

While it is true that certain factors can make the bowel more permeable, this probably does not lead to anything more than temporary mild inflammation of an area of the bowel.

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Why we should be sceptical about 'leaky gut syndrome'

Unproven theory

Exponents of 'leaky gut syndrome' – largely nutritionists and practitioners of complementary and alternative medicine – believe the bowel lining can become irritated and 'leaky' as the result of a much wider range of factors, including an overgrowth of yeast or bacteria in the bowel, a poor diet and the overuse of antibiotics.
They believe that undigested food particles, bacterial toxins and germs can pass through the 'leaky' gut wall and into the bloodstream, triggering the immune system and causing persistent inflammation throughout the body. This, they say, is linked to a much wider range of health problems and diseases, including:
food allergies
migraine
tiredness and chronic fatigue syndrome
asthma
autoimmune diseases (where the body's immune system attacks its own tissues) such as lupus, multiple sclerosis and rheumatoid arthritis
skin diseases like scleroderma
autism
The above theory is vague and currently largely unproven.

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