I'm primarily a D. I've been on Effexor for about a month. I am definely less anxious and certainly a lot happier. I haven't noticed like a severe change in my IBS symptoms but I've been pretty stable for most part. I've been following Heather's diet for 9 months now.. As far as side effects go sometimes I have headaches that I think are from the Effexor but other than that nothing else about them bothers me.