I am new to this site and do not know where to post this. I am desperate to figure out what is wrong with me. My colon does not know how to regulate my body's water. As a result, I am acutely and chronically dehydrated, to the point of total debilitation. I am being treated with standard IBS antidepressants, but hate the side effects. My doctor has no clue what is wrong with me. Does this sound remotely familiar to anyone??!!