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All Boards >> Irritable Bowel Syndrome Research Library

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HeatherAdministrator

Reged: 12/09/02
Posts: 7677
Loc: Seattle, WA
Herbs, Probiotics, and Supplements
      #13952 - 07/14/03 01:53 PM

All articles regarding herbs as medicine, probiotics, and other non-prescription supplements for IBS should be posted here.



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Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

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HeatherAdministrator

Reged: 12/09/02
Posts: 7677
Loc: Seattle, WA
Peppermint oil capsules for the treatment of IBS in children. new
      #13988 - 07/14/03 03:49 PM

J Pediatr. 2001 Jan;138(1):125-8.

Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children.

Kline RM, Kline JJ, Di Palma J, Barbero GJ.

University of Missouri-Columbia, Department of Child Health, Division of Pediatric Gastroenterology, Columbia, Missouri, USA.

In a randomized, double-blind controlled trial, 42 children with irritable bowel syndrome (IBS) were given pH-dependent, enteric-coated peppermint oil capsules or placebo. After 2 weeks, 75% of those receiving peppermint oil had reduced severity of pain associated with IBS. Peppermint oil may be used as a therapeutic agent during the symptomatic phase of IBS.

Publication Types:
Clinical Trial
Multicenter Study
Randomized Controlled Trial

PMID: 11148527 [PubMed - indexed for MEDLINE]

web page

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Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

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HeatherAdministrator

Reged: 12/09/02
Posts: 7677
Loc: Seattle, WA
Peppermint-oil capsules in the treatment of IBS: a prospective, randomized trial new
      #13989 - 07/14/03 03:51 PM

J Gastroenterol. 1997 Dec;32(6):765-8.

Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial.

Liu JH, Chen GH, Yeh HZ, Huang CK, Poon SK.

Department of Internal Medicine, Taichung Veterans General Hospital, Taiwan.

To determine the efficacy and tolerability of an enteric-coated peppermint-oil formulation (Colpermin), we conducted a prospective, randomized, double-blind, placebo-controlled clinical study in 110 outpatients (66 men/44 women; 18-70 years of age) with symptoms of irritable bowel syndrome. Patients took one capsule (Colpermin or placebo) three to four times daily, 15-30 min before meals, for 1 month. Fifty-two patients on Colpermin and 49 on placebo completed the study. Forty-one patients on Colpermin (79%) experienced an alleviation of the severity of abdominal pain (29 were pain-free); 43 (83%) had less abdominal distension, 43 (83%) had reduced stool frequency, 38 (73%) had fewer borborygmi, and 41 (79%) less flatulence. Corresponding figures for the placebo group were: 21 patients (43%) with reduced pain (4 were pain-free), 14 (29%) with reduced distension, 16 (32%) with reduced stool frequency, 15 (31%) with fewer borborygmi, and 11 (22%) with less flatulence. Symptom improvements after Colpermin were significantly better than after placebo (P < 0.05; Mann-Whitney U-test). One patient on Colpermin experienced heartburn (because of chewing the capsules) and one developed a mild transient skin rash. There were no significant changes in liver function test results. Thus, in this trial, Colpermin was effective and well tolerated.

Publication Types:
Clinical Trial
Randomized Controlled Trial

PMID: 9430014 [PubMed - indexed for MEDLINE]

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