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HeatherAdministrator

Reged: 12/09/02
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Loc: Seattle, WA
IBS quick tip -taking a fiber supplements and medications new
      #370106 - 08/30/13 11:54 AM

Can you take a soluble fiber supplement with medications?

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HeatherAdministrator

Reged: 12/09/02
Posts: 7679
Loc: Seattle, WA
IBS Quick Tip - Aloe, Senna, and Cascara for IBS? new
      #370159 - 09/10/13 11:20 AM

Aloe, Senna, and Cascara for IBS?

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HeatherAdministrator

Reged: 12/09/02
Posts: 7679
Loc: Seattle, WA
Vitamins and IBS new
      #370977 - 03/11/14 02:10 PM

Vitamins and IBS

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HeatherAdministrator

Reged: 12/09/02
Posts: 7679
Loc: Seattle, WA
Aloe vera in Patients with Irritable Bowel Syndrome new
      #372129 - 05/27/15 02:39 PM

ISRN Gastroenterol. 2011;2011:206103. doi: 10.5402/2011/206103. Epub 2010 Oct 11.

A Randomised, Cross-Over, Placebo-Controlled Study of Aloe vera in Patients with Irritable Bowel Syndrome: Effects on Patient Quality of Life.

Hutchings HA1, Wareham K, Baxter JN, Atherton P, Kingham JG, Duane P, Thomas L, Thomas M, Ch'ng CL, Williams JG.
Author information
Abstract

Background. Irritable bowel syndrome (IBS) is a chronic, difficult to treat condition. The efficacy of Aloe vera in treating IBS symptoms is not yet proven. The purpose of this study was to determine if Aloe vera is effective in improving quality of life. Methods. A multicentre, randomised, double-blind, cross-over placebo controlled study design. Patients were randomised to Aloe vera, wash-out, placebo or placebo, washout, Aloe vera. Each preparation (60 mL) was taken orally twice a day. Patient quality of life was measured using the Gastrointestinal Symptoms Rating Score, Irritable Bowel Syndrome Quality of Life, EuroQol and the Short-Form-12 at baseline and treatment periods 1 and 2. Results. A total of 110 patients were randomised, but only 47 completed all questionnaires and both study arms. Statistical analysis showed no difference between the placebo and Aloe vera treatment in quality of life. Discussion. This study was unable to show that Aloe vera was superior to placebo in improving quality of life. Drop outs and other confounding factors may have impacted on the power of the study to detect a clinically important difference. Conclusion. This study failed to find Aloe vera superior to placebo in improving quality of life proven Irritable Bowel Syndrome patients.

PMID:
21991499
[PubMed]
PMCID:
PMC3168391

http://www.ncbi.nlm.nih.gov/pubmed/21991499

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HeatherAdministrator

Reged: 12/09/02
Posts: 7679
Loc: Seattle, WA
Trial of aloe vera for irritable bowel syndrome new
      #372130 - 05/27/15 02:44 PM

Int J Clin Pract. 2006 Sep;60(9):1080-6. Epub 2006 Jun 2.
Randomised double-blind placebo-controlled trial of aloe vera for irritable bowel syndrome.

Davis K1, Philpott S, Kumar D, Mendall M.
Author information
Abstract

Aloe vera (AV) is suggested to be beneficial in treating irritable bowel syndrome (IBS) symptoms, but no scientific trials exist to confirm this. We aim to assess the efficacy of AV on IBS in refractory secondary care patients. Patients with IBS were randomised to receive AV or matching placebo for a month. Symptoms were assessed at baseline, 1 and 3 months. Fifty-eight patients randomised, 49 completed the protocol to 1 month and 41 to 3 months. Eleven of thirty-one (35%) AV patients, and 6 of 27 (22%) placebo patients responded at 1 month (p = 0.763). Diarrhoea predominant patients showed a trend towards a response to treatment at 1 month (10/23 V 2/14, p = 0.07). There was no evidence that AV benefits patients with IBS. However, we could not rule out the possibility that improvement occurred in patients with diarrhoea or alternating IBS whilst taking AV. Further investigations are warranted in patients with diarrhoea predominant IBS, in a less complex group of patients.

PMID:
16749917
[PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/pubmed/16749917

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HeatherAdministrator

Reged: 12/09/02
Posts: 7679
Loc: Seattle, WA
Vitamin D deficiency in children and adults with IBS new
      #373579 - 04/07/17 03:18 PM


New Medical Research Shows Vitamin D Deficiency Observed in Children, Adolescents and Adults with Irritable Bowel Syndrome (IBS), Calling Attention to Managing Nutritional Requirements Related to IBS

- New study notes that children and adolescents with Irritable Bowel Syndrome (IBS) have a high incidence of vitamin D deficiency

- Corroborates earlier evidence of vitamin D deficiency among adults with IBS

- Since vitamin D deficiency can lead to increased risk of decreased bone mass, nutritional requirements related to IBS need attention

- Intestinal malabsorption emerging as an underlying factor in IBS

News provided by
IM HealthScience

Apr 05, 2017, 09:04 ET

Share this article

BOCA RATON, Fla., April 5, 2017 /PRNewswire/ -- A recently published case-controlled study, entitled "Vitamin D status in pediatric irritable bowel syndrome,"1 found more than 90 percent of pediatric patients with Irritable Bowel Syndrome (IBS) were deficient in vitamin D. According to the lead study author from UMass Memorial Health Care, Benjamin U. Nwosu, M.D., these children "are definitely at risk for decreased bone mass." The study was published on February 13, 2017, in PLOS ONE, a peer-reviewed, open-access scientific journal published by the Public Library of Science (PLOS), which covers primary research within science and medicine.

Dr. Nwosu said that he "was surprised that IBS had the highest prevalence of vitamin D deficiency of all gastrointestinal disorders we have studied in the past 5 years."

The study authors noted, "There is a much higher prevalence of vitamin D deficiency (in IBS) compared to IBD (Inflammatory Bowel Disease) and other malabsorption syndromes."

"Clinicians should immediately increase their surveillance for vitamin D deficiency in patients with IBS and initiate appropriate vitamin D supplementation in cases of deficiency," said Dr. Nwosu.

Vitamin D Deficiency in Adults With IBS
A previous analysis in adults conducted with patients with IBS and a healthy control group without IBS, entitled "Vitamin D Deficiency in Patients with Irritable Bowel Syndrome: Does it Exist?"2, showed that vitamin D deficiency was highly prevalent in patients with IBS, and that vitamin D supplementation should be considered as part of the therapeutic protocol in patients with IBS. The 2015 study was published in the Oman Medical Journal, a peer-reviewed, open-access international journal.

Yasir Khayyat, M.D., the lead study author, concluded that vitamin D supplementation could play a therapeutic role in control of IBS. He said, "With an enhanced attention on the role of vitamin D deficiency in the pathogenesis of several chronic illnesses, deficiency of vitamin D in IBS has recently caught the interest of medical professionals. There have been numerous attempts of therapeutic application of vitamin D to improve IBS symptoms. More research is needed to establish the therapeutic role of vitamin D in the management of IBS patients and deficiency should be addressed in the diagnosis and the treatment of the condition."

Another double-blind, placebo-controlled pilot study recently was conducted by the University of Sheffield (U.K.). This study of adults with IBS, entitled "Vitamin D associates with improved quality of life in participants with irritable bowel syndrome: outcomes from a pilot trial,"3 showed that 78 percent of the IBS patients in the study were vitamin D deficient, and, at baseline, circulating vitamin D levels were correlated with IBS patients' quality of life. The lead author of the study, Simon Tazzyman, M.D., hypothesized that vitamin D supplementation may improve IBS symptoms. Study results revealed that vitamin D supplementation significantly improved vitamin D levels in both the placebo and vitamin D supplementation arms. However, in this study, the two arms did not separate when it came to IBS symptoms' severity. The 2016 study was published in the BMJ Open Gastroenterology, an online-only, peer-reviewed open access gastroenterology journal, dedicated to publishing high-quality medical research from all disciplines and therapeutic areas of gastroenterology.

http://www.prnewswire.com/news-releases/new-medical-research-shows-vitamin-d-deficiency-observed-in-children-adolescents-and-adults-with-irritable-bowel-syndrome-ibs-calling-attention-to-managing-nutritional-requirements-related-to-ibs-300434590.html

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Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

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HeatherAdministrator

Reged: 12/09/02
Posts: 7679
Loc: Seattle, WA
Review article: the physiological effects and safety of peppermint oil and its efficacy in irritable bowel syndrome new
      #373654 - 01/26/18 12:06 PM

Review article: the physiological effects and safety of peppermint oil and its efficacy in irritable bowel syndrome and other functional disorders
Authors

First published: 26 January 2018Full publication history
DOI: 10.1111/apt.14519 View/save citation

Summary
Background

Peppermint oil has been used for centuries as a treatment for gastrointestinal ailments. It has been shown to have several effects on gastrointestinal physiology relevant to clinical care and management.
Aim

To review the literature on peppermint oil regarding its metabolism, effects on gastrointestinal physiology, clinical use and efficacy, and safety.
Methods

We performed a PubMed literature search using the following terms individually or in combination: peppermint, peppermint oil, pharmacokinetics, menthol, oesophagus, stomach, small intestine, gallbladder, colon, transit, dyspepsia, nausea, abdominal pain, and irritable bowel syndrome. Full manuscripts evaluating peppermint oil that were published through 15 July 2017 were reviewed. When evaluating therapeutic indications, only randomised clinical trials were included. References from selected manuscripts were used if relevant.
Results

It appears that peppermint oil may have several mechanisms of action including: smooth muscle relaxation (via calcium channel blockade or direct enteric nervous system effects); visceral sensitivity modulation (via transient receptor potential cation channels); anti-microbial effects; anti-inflammatory activity; modulation of psychosocial distress. Peppermint oil has been found to affect oesophageal, gastric, small bowel, gall-bladder, and colonic physiology. It has been used to facilitate completion of colonoscopy and endoscopic retrograde cholangiopancreatography. Placebo controlled studies support its use in irritable bowel syndrome, functional dyspepsia, childhood functional abdominal pain, and post-operative nausea. Few adverse effects have been reported in peppermint oil trials.
Conclusion

Peppermint oil is a natural product which affects physiology throughout the gastrointestinal tract, has been used successfully for several clinical disorders, and appears to have a good safety profile.

Full article here http://onlinelibrary.wiley.com/doi/10.1111/apt.14519/full

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Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

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