Heather
()
05/11/07 02:19 PM
Bacterial flora in irritable bowel syndrome

Bacterial flora in irritable bowel syndrome: role in pathophysiology, implications for management


Author: QUIGLEY, Eamonn M M

Source: Chinese Journal of Digestive Diseases, Volume 8, Number 1, February 2007, pp. 2-7(6)

Publisher: Blackwell Publishing

Abstract:

Irritable bowel syndrome (IBS) may, in part at least, result from a dysfunctional interaction between the indigenous flora and the intestinal mucosa which, in turn, leads to immune activation in the colonic mucosa. Some propose a role for bacterial overgrowth as a common causative factor in the pathogenesis of symptoms in IBS; other evidence points to more subtle qualitative changes in the colonic flora; both hypotheses remain to be confirmed but the likelihood that bacterial overgrowth will prove to be a major factor in IBS now seems remote. Nevertheless, short-term therapy with either antibiotics or probiotics does seem to reduce symptoms among IBS patients. It seems most likely that the benefits of antibiotic therapy are mediated through subtle and, perhaps, localized, quantitative and/or qualitative changes in the colonic flora. How probiotics exert their effects remain to be defined but an anti-inflammatory effect seems likely. While this approach to the management of IBS is in its infancy, it is evident that manipulation of the flora, whether through the administration of antibiotics or probiotics, deserves further attention in IBS.

http://www.ingentaconnect.com/content/bsc/cdd/2007/00000008/00000001/art00002;jsessionid=1sugnl2qgrwj9.henrietta



| Privacy statement Help for IBS Home

*
UBB.threads™ 6.2

LEGAL DISCLAIMER - This website is not intended to replace the services of a physician, nor does it constitute a doctor-patient relationship. Information on this web site is provided for informational purposes only and is not a substitute for professional medical advice. You should not use the information on this web site for diagnosing or treating a medical or health condition. If you have or suspect you have an urgent medical problem, promptly contact your professional healthcare provider.

Any application of the recommendations in this website is at the reader's discretion. Heather Van Vorous, HelpForIBS.com, and Heather & Company for IBS, LLC are not liable for any direct or indirect claim, loss or damage resulting from use of this website and/or any web site(s) linked to/from it. Readers should consult their own physicians concerning the recommendations on these message boards.



Home | Shop for IBS | STORE FINDER | IBS Message Boards | IBS News & Reviews

IBS Diet | IBS Recipes | IBS Books | IBS Supplements | Yoga for IBS | Hypnosis for IBS
IBS Tummy Teas | Irritable Bowel Syndrome Glossary | IBS Symptoms
IBS Treatments | IBS Diet Plan | IBS Diarrhea | IBS Constipation
IBS Bloating & Stomach Gas | IBS Abdominal Pain

About Us | IBS Links | Search this Site | Site Map | Shipping & Returns | Privacy & Security
Contact Us | For Doctors & Dietitians | Wholesale | Co-packing Services

1999-2011, Heather Van Vorous, HelpForIBS.com, Heather & Company for IBS, LLC.
All information & art is proprietary and may not be duplicated.
All rights reserved.

Legal & Medical Disclaimer

Website Design